Must suppress the hype.
Bullet points from that:
-Qunari are a player race now, male and female.
-Top-down tactical menu is back, and available on console versions as well.
-Huge, varied maps where you actually see a civil war happening. So, unlike with Skyrim, you'll see battles, moving troops flanking enemy units, etc.
-Changing world according to your decisions. New towns will be founded, old towns will be destroyed, new towns will be destroyed, etc.
-New prompts on decisions explaining what the decision is (though not what it does), so you can't make one you don't understand. No more choosing "I don't think so..." and having your character stab someone in the throat for some reason.
-Environmental combat. You can use your enchanted weapons like spells for at least some (set fire to a boat, platform, etc.).
-Resource management. Health won't regenerate out of combat (though it's possible they'll be gear that does that I suppose). And health pots will be more limited in terms of number you can carry.
There's more - it's worth reading - that's just what's coming to mind.